Brain Regeneration: 12 Ways to Heal Brain Cells

Brain Regeneration: 12 Ways to Heal Brain Cells

Brain regeneration is an important concept that is critical in today’s environment.  Your brain is the command center of your nervous system and the center of all of your body’s functions and systems. The health of your brain is essential for your memory, learning, mental energy, and mood, and the prevention of mental health issues and neurodegenerative disorders. 

Even though most of your brain cells are formed in the womb and during infancy, new research suggests that your brain is able to regenerate and create new cells throughout your life. This means that you can keep your brain health, mental energy, and memory even as you age.

In this article, you will learn what brain regeneration, BDNF and neuroplasticity are and why are they important for brain health. You will understand the most common things that can damage your brain. I will also share 12 powerful ways to heal your brain cells and support your brain health naturally.

What is Brain Regeneration?

Your brain is one of your most important organs. It is the center of all of your body’s functions and systems. It serves as a command center for your nervous system that perceives stimuli, activates responses, and obtains and sends signals across your body to keep you safe and healthy. Your brain is also the place where your memory is stored and learning, cognition, and individual growth is happening.

Clearly, the health of your brain is critical and should be protected. You may think that it is normal for your brain to decline with age, however, that is not necessarily the case. Nutrition, lifestyle habits, and other factors all affect your brain health. More importantly, and contrary to old beliefs, your brain is able to generate new brain cells.

How Brain Regeneration Works

Most of your brain cells are formed while you were in your mother’s womb. Other neural cells of your brain developed during infancy. Until recent decades, doctors believed a certain level of brain degeneration is inevitable because your brain had a limited capacity to regenerate. Now we know better.

New research from the last two decades suggests that your brain is actually able to create new cells throughout your lifespan and brain regeneration is possible. Your brain actually still creates about 700 new neurons per day in the hippocampus. This allows the hippocampus to maintain its central function.

The science of neurogenesis suggests that aerobic exercise, brain exercises, stress relief, and other lifestyle habits can encourage brain regeneration, improve your brain health, and may help to prevent or treat degenerative diseases, such as Alzheimer’s and Parkinson’s disease, or reverse damage from traumatic brain injury (1, 2, 3, 4, 5, 6).

BDNF and Synaptic Plasticity

Brain-derived neurotrophic factor or BDNF is a protein produced inside your nerve cells to help your brain to communicate and function properly. It protects neurons, encourages their growth, improves their functions, and helps them to survive by protecting them from premature cell death. It also strengthens the signal between neurons by binding to the receptors at the synapses.

BDNF is essential for optimal brain function and a key player in brain regeneration. It plays an important role in learning and memory. It regulates various body functions, including eating and drinking. 

Brain Regeneration and Synaptic Density

Synapses are junctions between neurons that allow communication. Synaptic plasticity is the change that happens at synapses and affects the quality of the communication between two neurons. Short-term synaptic plasticity is a rapid, sub-second change that reverts to normal quickly.

Long-term synaptic plasticity is a longer change that may last for minutes, hours, days, or years. Long-term synaptic plasticity is critical for our brain’s ability to store information and for our memory. 

Research has shown that BDNF is critical for long-term enhancement of synaptic efficacy. It improves neural development and synaptic plasticity, hence it may lower the risk of neurodegenerative and psychiatric disorders, such as dementia, Alzheimer’s disease, Huntington disease, and depression (7, 8, 9, 10, 11, 12, 13).

Things That Damage Our Brain

Your diet, lifestyle, and overall health has everything to do with your brain health. Let’s take a look at the things that can damage our brain.

Blood Sugar Imbalances

Eating a diet high in processed carbs and refined sugar and low in vegetables, healthy fats, and clean protein can lead to blood sugar imbalances. Blood sugar imbalances may lead to irritability, lightheadedness, cravings, fatigue, mood fluctuations, memory issues, and brain fog.

You may experience constant cravings and fatigue. A quick carbohydrate-rich snack or meal may seem to give you quick energy, but soon, you will experience a sugar drop characterized by fatigue and brain fog. Blood sugar imbalances can increase your risk of diabetes, blood vessel problems, and compromised brain health (14, 15).

Environmental Toxicity

Toxins are everywhere. They are in our polluted air, our tap water, non-organic and processed foods, plastic products, moldy indoor spaces, and conventional beauty, body, and household products. Unfortunately, these environmental toxins may have a serious impact on our brain and overall health.

Neurotoxins, such as ethanol (in alcohol), glutamate, heavy metals, nitric oxide, botulinum toxin (in Botox), tetrodotoxin, and tetanus toxin, are particularly damaging to your neurological health. Environmental toxicity may increase brain fog, memory problems, anxiety, depression, mental health issues, fatigue, mood swings, irritability, dementia, and neurodegenerative diseases (16, 17, 18).

Sedentary Lifestyle

Movement is, of course, critical for your health. But it’s more than your physical strength, toned look, or cardiovascular fitness. Movement is crucial for your brain health as well, especially for those areas of your brain that are important for memory formation.

A sedentary lifestyle causes brain cell degeneration.  Research has found that a sedentary lifestyle may increase your risk of memory problems, learning troubles, and cognitive decline (19, 20).  

Chronic Stress and Poor Sleep Habits

When you are experiencing stress, the amygdala, the area in your brain that partakes in emotional processing, signals your hypothalamus. As a response, your hypothalamus increases your heart rate encourages deeper intake of oxygen and heavier breathing, heightens your senses, rushes adrenaline in your body, and increases your cortisol levels. When the stress is over, everything should return to normal. However, when you are under stress, this stress response is never over.

Chronic stress leads to a build-up of cortisol in the body. Among many other functions, cortisol helps your hippocampus, where your memories are stored and processed. When you are under chronic stress and there is too much cortisol, it wears your brain down, impairs brain and memory function, disrupts synapse regulation, and kills brain cells. Chronic stress has a seriously negative effect on your memory and learning (21, 22, 23).

Regular poor sleep can also have a serious impact on your brain health. It may increase chronic stress, fatigue, and chronic inflammation, which may lead to brain fog, memory troubles, mood swings, low mood, and learning difficulties. According to research, sleep deprivation may even increase the risk of dementia and Alzheimer’s disease (24, 25, 26). 

Gut Infections and Dysbiosis

Have you ever experienced stomach problems before an important event, public speaking, or a new date? The connection between our brain and our gut is clear. However, our gut and brain not only affect each other short-term during stressful or exciting events. The communication between the two is on-going, long-term, and intimate.

Gut dysbiosis and gut infections can increase inflammation in the gut and the entire body. Chronic inflammation affects your entire body, not just your brain. Gut microbiome imbalance to mood cognition, and mental health. Digestive problems, gut dysbiosis, and gut infections may increase your risk and symptoms of brain fog, memory problems, learning difficulties, anxiety, depression, and neurodegenerative diseases (27, 28, 29).

Top 12 Brain Regeneration Strategies

Chances are, you want to say good-bye to brain fog, memory issues, learning troubles, mental fatigue, and low mood. You certainly want to protect your brain from neurodegeneration, dementia, and Alzheimer’s disease.

Read on to learn the top 12 ways to protect and heal your brain cells naturally.  Practicing some form of all of these strategies is important for optimizing your mental health and keeping your brain healthy and strong.

Anti-Inflammatory Diet

Eating an anti-inflammatory diet rich in nutrient-dense foods is critical for your brain health. Begin by removing all inflammatory foods, including refined sugar, gluten, refined oils, deep-fried and processed foods, conventional dairy, grain-fed meat and eggs, soda and sugary drinks, and foods that you are sensitive to.

Instead, eat an anti-inflammatory diet with lots of greens, vegetables, low glycemic index fruits, herbs, spices, healthy fats, grass-fed meat, and wild-caught fish. To learn more about an anti-inflammatory diet, read this article as well. 

Intermittent Fasting

Intermittent fasting is a fasting strategy that cycles between fasting and eating over a period of time. It helps cellular repair, autophagy, immune regulation, inflammation levels, and insulin sensitivity, and decreases the risk of chronic diseases, including neurodegenerative conditions, such as Alzheimer’s.

Spiritual leaders and philosophers such as Plato have talked about the benefits of fasting on improving mental efficiency, creativity, intuition and sense of well-being.  If you want to learn more about the benefits of intermittent fasting and how to practice intermittent fasting, I recommend this article.

Getting Into Ketosis From Time to Time

Under the regular circumstances, most people’s body creates energy by breaking down glucose from dietary carbohydrates. However, when your body doesn’t receive enough glucose supply, it turns to dietary or stored body fat for energy. These fats are converted in the liver into ketones that enter your mitochondria inside your cells to be turned into energy.

This process of ketosis helps to enhance autophagy, reduce inflammation, improve mitochondrial biogenesis, improve brain health, and increase mental sharpness. The best way to experience ketosis is through the combination of the keto diet and intermittent fasting. 

I am not saying you have to follow a ketogenic diet all the time, you can vary your nutrition, but actively working to get into ketosis from time to time is extremely beneficial for brain regeneration.  To learn more about ketosis, I recommend this article, and to learn more about how the keto diet improves brain health, read this one (31, 32, 33, 34, 35, 36, 37, 38 39, 40).

Regular Movement and Exercise

As you’ve learned earlier, regular movement and exercise are not only part of a healthy lifestyle, but are essential for brain health. They may help to lower chronic inflammation, reduce stress levels, and decrease the risk of memory problems, learning troubles, and cognitive decline.

I recommend that you exercise at least 20 to 30 minutes minimally 5 times a week. Try a combination of cardiovascular exercise, strength and resistance training, and low-impact exercise. Aim to stay active throughout the day by choosing to take the stairs, taking a walk at lunch, stretching regularly, gardening, and dancing for your favorite song. 

Reduce Stress and Practice Gratitude

Reducing your stress levels is non-negotiable for brain regeneration and mental health. To reduce your stress, try regular meditation, daily prayer, breathwork, journaling, regular exercise, relaxation recordings, daily gratitude, and nature walks. Practice positive self-talk and affirmations for a powerful mindset and mood shift.

Practice daily gratitude and prayer. Keep a daily gratitude journal and count your blessing throughout the day. Remember, when you are in a state of gratitude, negative energy, stress, and anxiety have no room.

Prioritize Good Sleep

Prioritizing good-quality sleep is critical for your brain regeneration and mental health. It is essential for rest, repair, and cellular rejuvenation. Develop a regular nighttime routine that relaxes your body before sleep and works for you. Avoid sugar and caffeine throughout the day, especially in the evening.

Turn off your electronics several hours before bedtime. Engage in relaxing activities. Meditate, journal, reading, read, stretch, and sip on some herbal tea. Make sure that you have a comfortable bed, bedding, and pillows. Try some black-out curtains or a sleep mask.

Support Gut Health

As you’ve learned, your brain and gut are closely connected, hence supporting your gut is absolutely necessary to heal your brain cells. Eating a gut-friendly, anti-inflammatory, and nutrient-dense diet is a must.

Additionally, support a gut microbiome balance with healthy bacteria by eating probiotic-rich foods, such as sauerkraut, kimchi, and kefir, and taking a daily probiotic supplement.

Neurobic Exercises 

Neurobics is a term used to describe the physiological effects of unique and non-routine ways of thinking and moving and their effects on the brain to improve memory, learning, mood, and mindset.  These exercises can help stimulate brain regeneration by challenging the brain to think and move in unique ways.  

Neurobics exercises include balancing on one leg, crossword puzzles, trying a new instrument, using your non-dominant hand, barefoot walking, and journaling. To learn more about the benefits of neurotics exercises, I read this article (41, 42, 43, 44, 45).

Reduce Your Toxic Load

To optimize your brain health, you cannot forget about reducing your toxic load. Eat organic foods as much as possible. Remove conventional beauty, body, and household products, and replace them with organic, natural, or homemade alternatives.

Spend time in nature as much as possible.  Getting good water filtration is also especially important.  You can also get a quality Berkey filter or take it up a notch and use a hydrogen water system which adds molecular hydrogen to combat oxidative stress and improve immune health.

Use Magnesium

One of the key nutrients to address for proper brain regeneration is magnesium.  Magnesium is critical for brain health, mental health, relaxation, and stress relief.

I recommend Brain Calm Magnesium to boost your magnesium levels. It helps muscle function, healthy nerve conduction, neurological function, energy production, mood, and mental health. Dissolve one scoop in 6 oz of cool, pure water. Take it once a day at night.

Use Autophagy Enhancing Herbs 

Autophagy is your body’s natural method of detoxification. It allows your body to recycle and get rid of old and unhealthy cells leaving room for the creation of new and healthy cells to replace them. To heal your brain cells, I recommend autophagy-enhancing herbs, including matcha green tea, ginger, turmeric, resveratrol, citrus bergamot, oregano, sage, rosemary, and quercetin.

This is why I recommend Inflam Defense™, a powerful supplement made with turmeric, ginger, boswellia, quercetin, rosemary, and rutin. To learn more about the top autophagy-enhancing herbs, I recommend this article.

Use Mitochondrial Support Nutrients  

For optimal brain health, I also recommend that you support your mitochondrial health. Mito Support™ was designed to support the function of the mitochondria, which is the powerhouse of your cell and the key cellular health.

It is a blend of nutrients, nutraceuticals, botanicals, and Krebs cycle intermediates designed to support efficient mitochondrial metabolism and energy (ATP) production for increased vitality. It supports brain health, cognition, mental health, and healthy energy levels.  Supporting your mitochondria is a key principle for brain regeneration.  

Bonus: Consider Hyperbaric Oxygen Therapy

For additional support, consider hyperbaric oxygen therapy. It has been shown to raise tissue oxygen levels, encourage new blood vessel growth, increase your body’s defense system, reduce swelling, increase stem cells, and support optimal health.

Brain regeneration can be enhanced with the use of hyperbaric oxygen therapy on a regular basis.  To learn more about hyperbaric oxygen therapy, I recommend reading this article (47, 48, 49, 50, 51).

Final Thoughts on Brain Regeneration

Your brain health is essential for memory, learning, mental sharpness, mood, and mental health. The good news is that your brain is able to regenerate and create new cells throughout your life. 

Brain regeneration is a powerful topic that should empower us to live at a higher level. Follow my 12 tips to heal your brain cells and support your brain health naturally.  For more info on how to activate your body’s innate healing ability, check out my free Brain Regeneration Guide.

If you want to work with a functional health coach, I recommend this article with tips on how to find a great coach. On our website, we offer long-distance functional health coaching programs. For further support with your health goals, just reach out—our fantastic coaches are here to support your journey.

Inflammation Crushing Ebundle

The Inflammation Crushing Ebundle is designed to help you improve your brain, liver, immune system and discover the healing strategies, foods and recipes to burn fat, reduce inflammation and Thrive in Life!

As a doctor of natural medicine, I have spent the past 20 years studying the best healing strategies and worked with hundreds of coaching clients, helping them overcome chronic health conditions and optimize their overall health.

In our Inflammation Crushing Ebundle, I have put together my very best strategies to reduce inflammation and optimize your healing potential.  Take a look at what you will get inside these valuable guides below!

Sources in This Article Include:

1. Can you grow new brain cells? Harvard Medical School. Link Here

2. Ernst A, Frisén J. Adult neurogenesis in humans- common and unique traits in mammals. PLoS Biol. 2015;13(1):e1002045. Link Here

3. Erickson KI, Voss MW, Prakash RS, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci USA. 2011 Link Here

4. Sorrells SF, Paredes MF, Cebrian-silla A, et al. Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature. 2018;555(7696):377-381. Link Here

5. Martino G, Pluchino S, Bonfanti L, Schwartz M. Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiol Rev. 2011 Oct;91(4):1281-304. doi: 10.1152/physrev.00032.2010. PMID: 22013212

6. Liaw K, Zhang Z, Kannan S, Neuronanotechnology for brain regeneration, Advanced Drug Delivery Reviews, Volume 148, 2019, Pages 3-18. Link Here

7. What is synaptic plasticity. Queenland Brain Institute. Link Here

8. Cunha C, Brambilla R, Thomas KL. A simple role for BDNF in learning and memory? Front Mol Neurosci. 2010 Feb 9;3:1. doi: 10.3389/neuro.02.001.2010. PMID: 20162032

9. Lu B. BDNF and synaptic plasticity, cognitive function, and dysfunction. Handb Exp Pharmacol. 2014;220:223-5. PMID: 24668475 

10. Lel G, Bamrham CH, Duarte CB. BDNF and Hippocampal Synaptic Plasticity. Vitam Horm. 2017;104:153-195. PMID:  28215294 

11. Bramham CR, Messaoudi E. BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis,Progress in Neurobiology,Volume 76, Issue 2, 2005, Pages 99-125. Link Here

12. Bathina S, Das UN. Brain-derived neurotrophic factor and its clinical implications. Arch Med Sci. 2015 Dec 10;11(6):1164-78. doi: 10.5114/aoms.2015.56342. Epub 2015 Dec 11. PMID: 2678807

13. BNDF gene. Genetics Home Reference. Link Here

14. How diabetes affects your brain. Web MD. Link Here

15. Blood sugar on the brain. Harvard Health Publishing. Link Here

16. Yegambaram M, Manivannan B, Beach TG, Halden RU. Role of environmental contaminants in the etiology of Alzheimer’s disease: a review. Curr Alzheimer Res. 2015;12(2):116-46. doi: 10.2174/1567205012666150204121719. PMID: 25654508

17. Taking it all in: Environmental toxins and your health. Link Here

18. Liu J, Lewis G. Environmental toxicity and poor cognitive outcomes in children and adults. J Environ Health. 2014 Jan-Feb;76(6):130-8. PMID: 24645424

19. Wheeler MJ, Dempsey PC, Grace MS, Ellis KA, Gardiner PA, Green DJ, Dunstan DW. Sedentary behavior as a risk factor for cognitive decline? A focus on the influence of glycemic control in brain health. Alzheimers Dement (N Y). 2017 May 2;3(3):291-300. doi: 10.1016/j.trci.2017.04.001. PMID: 29067335

20. Sitting is bad for your brain — not just your metabolism or heart: Thinning in brain regions important for memory linked to sedentary habits. University of California, Los Angeles. ScienceDaily. Link Here

21. Van der Kooij MA, Fantin M, Rejmak E, Grosse J, Zanoletti O, Fournier C,Ganguly K,Kalita K, Kaczmarek L, Sandi C. Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations. Nature Communications, 2014; 5: 4995. Link Here

22. Stress kills brain cells. Scientific American. Link Here

23. How stress and depression can shrink the brain. Yale University. ScienceDaily. ScienceDaily, 12 August 2012. Link Here

24. Holth JK, Fritschi SK, Wang C, Pedersen NP, Cirrito JR, Mahan TE, Finn MB, Manis M, Geerling JC, Fuller PM, Lucey BP, Holtzman DM. The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans. Science, 2019.

25. The sleep deprived brain. Dana Foundation. Link Here

26. Zhao Z, Zhao X, Veasey SC. Neural Consequences of Chronic Short Sleep: Reversible or Lasting? Front Neurol. 2017 May 31;8:235. doi: 10.3389/fneur.2017.00235. PMID: 28620347

27. Lucas G. Gut thinking: the gut microbiome and mental health beyond the head. Microb Ecol Health Dis. 2018 Nov 30;29(2):1548250. doi: 10.1080/16512235.2018.1548250. PMID: 30532687

28. Appleton J. The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health. Integr Med (Encinitas). 2018 Aug;17(4):28-32. PMID: 31043907

Rogers GB, Keating DJ, Young RL, Wong ML, Licinio J, Wesselingh S. From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways. Mol Psychiatry. 2016 Jun;21(6):738-48. doi: 10.1038/mp.2016.50. Epub 2016 Apr 19. PMID: 27090305

29. Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: The gut-brain axis. Clin Pract. 2017 Sep 15;7(4):987. doi: 10.4081/cp.2017.987. PMID: 29071061

30. Faris MA, Kacimi S, Al-Kurd RA, Fararjeh MA, Bustanji YK, Mohammad MK, Sale ML. Intermittent fasting during Ramadan attenuates proinflammatory cytokines and immune cells in healthy subjects. Nutr Res. 2012 Dec;32(12):947-55. PMID: 23244540

31. Vasconcelos AR, Yshii LM, Viel TA, et al. Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment. Journal of Neuroinflammation. 2-14;11:85

32. Aksungar FB, Topkaya AE, Akyildiz M. Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting. Ann Nutr Metab. PMID: 17374948

33. Hirao Kohno, Katsuyasu Kouda, Hiroyasu Ishihara, Nobuhiro Nishio,Yutaka Sasaki, Harunobu Nakamura, Masayuki Iki, Yoshiaki Sonoda. Intermittent Fasting Ameliorates Delayed-Type Hypersensitivity in NC/Nga Mice. Food and Nutrition Sciences2011, 2, 287-293 Published Online June 2011 Copyright © 2011 SciRes. Link Here

34. Alirezaei M, Kemball CC, Flynn CT, Wood MR, Whitton JL, Kiosses WB. Short-term fasting induces profound neuronal autophagy. Autophagy. 2010;6(6):702-710.

35. Anderson JL, Carlquist JF, Roberts WL, Horne BD, May HT, Schwarz EL, Pasquali M, Nielson R, Kushnir MM, Rockwood AL, Bair TL, Muhlestein JB; Intermountain Heart Collaborative Study Group.. Asymmetric dimethylarginine, cortisol/cortisone ratio, and C-peptide: markers for diabetes and cardiovascular risk? Am Heart J. 2007 Jan;153(1):67-73. PMID: 17174641

36. Lanzi R, Luzi L, Caumo A, Andreotti AC, Manzoni MF, Malighetti ME, Sereni LP, Pontiroli AE. Elevated insulin levels contribute to the reduced growth hormone (GH) response to GH-releasing hormone in obese subjects. Metabolism. 1999 Sep;48(9):1152-6. PubMed PMID: 10484056

37. Ji S, Guan R, Frank SJ, Messina JL. Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway. J Biol Chem. 1999 May 7;274(19):13434-42. PMID: 10224108

38. Varady KA, Hellerstein MK. Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr. 2007 Jul;86(1):7-13. PMID: 17616757

39. Buschemeyer WC 3rd, Klink JC, Mavropoulos JC, Poulton SH, Demark-Wahnefried W, Hursting SD, Cohen P, Hwang D, Johnson TL, Freedland SJ. Effect of intermittent fasting with or without caloric restriction on prostate cancer growth and survival in SCID mice. Prostate. 2010 Jul 1;70(10):1037-43. PMID: 20166128

40. Rogozina OP, Nkhata KJ, Nagle EJ, Grande JP, Cleary MP. The Protective Effect of Intermittent Calorie Restriction on Mammary Tumorigenesis is Not Compromised by Consumption of a High Fat Diet During Refeeding. Breast cancer research and treatment. 2013;138(2):395-406.

41. Götz M, Huttner WB. The cell biology of neurogenesis. Nat Rev Mol Cell Biol. 2005 Oct;6(10):777-88. PMID: 16314867

42. Yamada K Mizuno M, Nabeshima, T. Role for brain-derived neurotrophic factor in learning and memory. Life Sci. 2002 Jan 4;70(7):735-44. PMID: 11833737

43. O’Bryant SE, Hobson V, Hall JR, Waring SC, Chan W, Massman P, Lacritz L, Cullum CM, Diaz-Arrastia R; Brain-derived neurotrophic factor levels in Alzheimer’s disease. Texas Alzheimer’s Research Consortium. J Alzheimers Dis. 2009;17(2):337-41. PMID: 19363274

44. Role of brain-derived neurotrophic factor in Huntington’s disease (PDF)

45. Clough RL, Sud R, Davis-Silberman N, Hertzano R, Avraham KB, Holley M, Dawson 

46. Tompach PC, Lew D, Stoll JL. Cell response to hyperbaric oxygen treatment. Int J Oral Maxillofac Surg. 1997 Apr;26(2):82-6. PMID: 9151158

47. Thackham JA, McElwain DL, Long RJ. The use of hyperbaric oxygen therapy to treat chronic wounds: A review. Wound Repair Regen. 2008 May-Jun;16(3):321-30. PMID: 18471250

48. Conconi MT, Baiguera S, Guidolin D, Furlan C, Menti AM, Vigolo S, Belloni AS, Parnigotto PP, Nussdorfer GG. Effects of hyperbaric oxygen on proliferative and apoptotic activities and reactive oxygen species generation in mouse fibroblast 3T3/J2 cell line. J Investig Med. 2003 Jul;51(4):227-32. PMID: 12929739

49. Heyboer M 3rd, Milovanova TN, Wojcik S, Grant W, Chin M, Hardy KR, Lambert DS, Logue C, Thom SR. CD34+/CD45-dim stem cell mobilization by hyperbaric oxygen – changes with oxygen dosage. Stem Cell Res. 2014 May;12(3):638-45. PMID: 24642336

50. Yang YJ, Wang XL, Yu XH, Wang X, Xie M, Liu CT. Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-ischemic brain damage in neonatal rats. Undersea Hyperb Med. 2008 Mar-Apr;35(2):113-29. PMID: 18500076

51. Wang XL, Yang YJ, Xie M, Yu XH, Wang QH. [Hyperbaric oxygen promotes the migration and differentiation of endogenous neural stem cells in neonatal rats with hypoxic-ischemic brain damage]. Zhongguo Dang Dai Er Ke Za Zhi. 2009 Sep;11(9):749-52. PMID: 19755026