Measuring Your C Reactive Protein Levels

  • FDA Disclaimer
    The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. Learn More
  • Affliliate Disclosure
    In compliance with the FTC guidelines, please assume the following about links and posts on this site: Many of the links on DrJockers.com are affiliate links of which I receive a small commission from sales of certain items, but the price is the same for you. If I post an affiliate link to a product, it is something that I personally use, support and would recommend without an affiliate link. Learn More
  • Privacy Policy
    Please read the Privacy Policy carefully before you start to use DrJockers.com. By using DrJockers.com or by clicking to accept or agree to Terms of Use when this option is made available to you, you accept and agree to be bound and abide by the Privacy Policy. Learn More
Print Friendly, PDF & Email

c reactive protein

Measuring Your C Reactive Protein Levels:

Most doctors have been misled to focus on total cholesterol as a key figure in measuring heart disease.  More recent research has shown that measuring inflammatory mediators and inflammatory levels in the body is a much better way of assessing cardiovascular risk.  C Reactive Protein (CRP) is one of the major inflammatory markers that should be measured when assessing inflammatory levels and risk of heart disease (1, 2, 3).

CRP is released from the liver in response to acute tissue damage and inflammation.  It is activated by macrophages and adipocytes in order to bind phosphocholine expressed on the surface of dead or dying cells in order to activate the C1Q complement part of the immune system.  This means that it helps drive up inflammatory activity in the body.

Cardiovascular Disease and Inflammatory 

Heart disease is characterized by chronic inflammatory activity in the cardiac tissue and major arterial beds of the body.  This chronic inflammation causes scar tissue and plaque to build up in the arterioles as well as blood clotting to form.

This leads overtime to myocardial and cerebral infractions.  Studies have indicated that individuals with elevated levels of CRP have a risk about 2-3 times higher than the risk of those with low levels (4, 5).  Over a dozen major studies have shown a link between apparently healthy men and women and their future risk of cardiovascular events with higher levels of CRP (6, 7).

It is also been shown that CRP levels predict the risk of recurrent coronary events among patients who already have cardiovascular disease.  The most important use of CRP is in detecting risk among individuals who do not know they have a problem (8).

CRP and Metabolic Disease:

Individuals with CRP levels greater than 3 mg/L have a four to six time higher risk of developing diabetes than individuals with lower levels of CRP.  This is another indication of the link between chronic inflammation and diabetes, obesity and heart disease.  Many physicians include CRP levels in the diagnostic criteria for metabolic syndrome (9, 10).

We use to think that obesity was solely related to eating too much and moving too little.  Now, we understand that obesity is a condition characterized by chronic inflammatory activity in the body.  Excess fat tissue is not dormant and metabolically inactive (11, 12).

It, instead, is constantly promoting the release of pro-inflammatory proteins and chemicals.  The fat (adipose) tissue itself, actively contributes to the inflammatory processes.  This creates a vicious cycle within the body that makes it more challenging for these individuals to get well.

c reactive protein

Best Cardiovascular Panels:

It is very advantageous to look at CRP along with a number of other risk factors for cardiovascular disease.  These include things like homocysteine and lipoprotein (a) as well as a basic lipid panel.

More advanced panels will include a Vertical AutoProfile (VAP) test that looks in much more detail at the lipid subtypes as does the NMR (Nuclear Magnetic Resonance) lipid profile.

clogged arteries, Clogged Arteries: Causes, Symptoms & Support Strategies

Normal vs Pathological CRP Ranges:

The key test for CRP levels is a “high sensitivity” test also called hs-CRP.  The standard CRP test does not have the ability to measure levels accurately within the range needed for cardiac risk detection.  Normal ranges are considered to be under 3.0 mg/L (13, 14).

Functional healthy ranges are under 2 mg/L.  If one has an active infection or tissue trauma they will have higher hs-CRP levels and the test should be run again when the trauma or infection has been healed.

High-sensitivity CRP usually is ordered as one of several tests in a cardiovascular risk profile, often along with tests for cholesterol and triglycerides, when a person’s risk of heart disease is being evaluated.   Some experts say that the best way to predict risk is to combine a good marker for inflammation, like hs-CRP, along with the lipid profile (15).

When hs-CRP is evaluated, it may be repeated to confirm that a person has persistent low levels of inflammation.  We recommend our CardioPower test which looks in detail at all the key biomarkers involved with inflammation and a healthy cardiovascular system.  We also include hs-CRP in our Comprehensive Blood Analysis.

For more information on how to reduce inflammation in the body, check out this article.

C Reactive Protein

Most people don’t know this but…

Almost half of all American adults now have high blood pressure!

>> Find Out How to Lower Your Blood Pressure Naturally

Why is this such a big deal?

Because high blood pressure is the precursor to some of the very worst health outcomes…

  • Heart attacks
  • Strokes
  • Aneurysms
  • Kidney disease
  • Vascular dementia
  • Vision loss
  • Heart failure

Many people believe that “these things just happen as you age.”

I say “nonsense!” to that line of thinking!

You can easily avoid some of the most common health disasters by lowering your blood pressure using the 18 simple (and delicious!) methods found in this new ebook:

Getting your blood pressure back down into the HEALTHY range could be as easy as…

Upgrading your breakfast routine with a few “functional fruits” or…

As simple as “jazzing up” your meals with some heart-healthy herbs and spices.

So, starting today, you can take these simple steps to protect your health!

…and you’ll also get the chance to save your seat to watch the Cardiovascular Docu-Class hosted by my good friend, Jonathan Landsman.

This event features 32 presentations from 22 of the world’s brightest minds in heart health.

Check out this schedule of all the amazing topics being covered and you’ll soon realize just how important it is for you to attend.

Armed with this cutting-edge heart health information, you won’t need to fear the world’s #1 killer any longer.

Inflammation Crushing Ebundle

The Inflammation Crushing Ebundle is designed to help you improve your brain, liver, immune system and discover the healing strategies, foods and recipes to burn fat, reduce inflammation and Thrive in Life!

As a doctor of natural medicine, I have spent the past 20 years studying the best healing strategies and worked with hundreds of coaching clients, helping them overcome chronic health conditions and optimize their overall health.

In our Inflammation Crushing Ebundle, I have put together my very best strategies to reduce inflammation and optimize your healing potential.  Take a look at what you will get inside these valuable guides below!

Sources For This Article Include:

1. Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, Lowe GD, Pepys MB, Gudnason V. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med. 2004 Apr 1;350(14):1387-97. PMID: 15070788
2. The New England Journal of Medicine – C-Reactive Protein Reassessed Link Here
3. The New England Journal of Medicine – C-Reactive Protein and Coronary Heart Disease Link Here
4. Koenig W, Sund M, Fröhlich M, Fischer HG, Löwel H, Döring A, Hutchinson WL, Pepys MB. C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992. Circulation. 1999 Jan 19;99(2):237-42. PMID: 9892589
5. The New England Journal of Medicine – C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease Link Here
6. Haim M, Benderly M, Tanne D, Matas Z, Boyko V, Fisman EZ, Tenenbaum A, Zimmlichman R, Battler A, Goldbourt U, Behar S. C-reactive protein, bezafibrate, and recurrent coronary events in patients with chronic coronary heart disease. Am Heart J. 2007 Dec;154(6):1095-101. PMID: 18035081
7. Blake GJ, Ridker PM. Inflammatory bio-markers and cardiovascular risk prediction. J Intern Med. 2002 Oct;252(4):283-94. PMID: 12366601
8. Ogiwara F, Takahashi M, Ikeda U. [Inflammatory markers and cytokines in cardiovascular disease]. Rinsho Byori. 2004 Aug;52(8):686-92. PMID: 15478624
9. Devaraj S, Singh U, Jialal I. Human C reactive protein and the metabolic syndrome. Curr Opin Lipidol. 2009 Jun;20(3):182-9. PMID: 19369869
10. Ndumele CE, Pradhan AD, Ridker PM. Interrelationships between inflammation, C reactive protein, and insulin resistance. J Cardiometab Syndr. 2006 Summer;1(3):190-6. PMID: 17679826
11. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C reactive protein levels in overweight and obese adults. JAMA. 1999 Dec 8;282(22):2131-5. PMID: 10591334
12. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Low-grade systemic inflammation in overweight children. Pediatrics. 2001 Jan;107(1):E13. PMID: 11134477
13. Ridker PM. Cardiology Patient Page. C reactive protein: a simple test to help predict risk of heart attack and stroke. Circulation. 2003 Sep 23;108(12):e81-5. PMID: 14504253
14. Ridker PM. High-sensitivity C reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation. 2001 Apr 3;103(13):1813-8. PMID: 11282915
15. Whelton SP, Roy P, Astor BC, Zhang L, Hoogeveen RC, Ballantyne CM, Coresh J. Elevated high-sensitivity C-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age. The ARIC Study. Am J Epidemiol. 2013 Oct 1;178(7):1076-84. PMID: 24026395

c reactive protein

Was this article helpful?
YesNo
Dr. Jockers

Dr David Jockers is passionate about seeing people reach their health potential in mind, body and spirit. He is the host of the popular “Dr Jockers Functional Nutrition” podcast and the author of the best-selling books, “The Keto Metabolic Breakthrough” and “The Fasting Transformation.”

Categories

Heart Health

Let's Improve Your Health Today!

Get instant access to 2 FREE eBooks when you subscribe to Dr. Jockers’ newsletter.

ebooks

"Join my tribe today to discover hidden strategies to improve your energy, brain, digestion & metabolism."

— Dr. David Jockers
Dr Jockers

Comments

comments

Comments

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.