The Great Cholesterol Myth

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cholesterol myth, The Great Cholesterol Myth

cholesterol myth, The Great Cholesterol Myth

The Cholesterol Myth

There are many common & accepted understandings within modern culture that have no true scientific basis, but have just merely been accepted as fact. One of the major issues has to do with the pathogenesis of various common diseases including heart disease and cancer.  This article will go into the cholesterol myth and how exactly it came to be.

Cholesterol has been vilified as the major cause of heart disease.  The claim that it clogs our arteries is known world-wide, despite no scientific evidence to validate the idea.  As a society, we need to retrain our doctors and clinicians to look at this “cholesterol theory” with a skeptical eye.

cholesterol myth, The Great Cholesterol Myth

The Birth of Heart Disease and The Cholesterol Myth

Heart disease was considered a very rare disease in the early 20th century.  However, as food processing began to take off so did the occurrence of heart disease.  By the 1950’s, it was considered a major health threat.  Over the last 50 years, a whole arsenal of drugs and surgeries has been developed to address this increasingly growing disorder (1).

Today, despite trillions of dollars of research and the best medical equipment available, the American Heart Association said in 2012 that Americans have a 48% chance of getting this deadly disease (2).

cholesterol myth, The Great Cholesterol Myth

The Lipid Hypothesis and The Cholesterol Myth:

Developed by Ancel Keys in the 1950’s, this theory states that there is a direct relationship between the amount of saturated fat and cholesterol in the diet and the incidence of coronary heart disease.  With questionable evidence, Keys’ went about writing articles and promoting this hypothesis throughout the medical world (3).

Meanwhile, hundreds of subsequent studies testing this hypothesis have found differing conclusions. Despite the lack of evidence, this notion took off throughout the healthcare world and was fueled by the vegetable oil and food processing industries that sought to benefit from this finding.  This is the foundation for the cholesterol myth that many believe today.

cholesterol myth, The Great Cholesterol Myth


The New Science of Heart Disease:

Close to 90% of all well-planned, properly documented studies investigating the lipid hypothesis do not support the claim that “artery-clogging” saturated fats and dietary cholesterol cause heart disease (4, 5, 6).

In a 1994 study in the British medical journal Lancet, London researchers analyzed the fat they found in clogged arteries. It turns out only 26% of it was saturated animal fat. The other 74% was unsaturated. That’s the same type of fat you find in “heart healthy” canola oil (7).

So the majority of the fat within a clogged artery is not saturated fat and cholesterol.  Additionally, calcium is a major player in arterial plaque and yet very rarely is this discussed.

cholesterol myth, The Great Cholesterol Myth

The Benefits of Saturated Fat & Cholesterol

Most doctors are uneducated on this topic and continue to teach the cholesterol myth.  But according to Dr. Mary Enig, PhD, an expert in lipid biochemistry, her extensive research on the roles of saturated fat and cholesterol in our bodies and the intake of these compounds in our diet(8):

1.  Cell Membrane Health:  Saturated fatty acids and cholesterol constitute at least 50% of the cell membranes. They are what gives our cells necessary stiffness and integrity.

2.  Bone Health:  They play a vital role in the health of our bones. For calcium to be effectively incorporated into the skeletal structure, at least 50% of the dietary fats should be saturated.   Cholesterol is the precursor to vitamin D & major hormones that regulate stress, energy & sex hormone (estrogen, progesterone, DHEA, testosterone, etc) function.

3.  Lower Lp (a):  They lower Lp(a), a substance in the blood that indicates proneness to heart disease. They protect the liver from alcohol and other toxins, such as Tylenol.

4.  Enhance Immunity:  They enhance the immune system and act as an anti-depressant by enhancing serotonin receptor function.  Low cholesterol is highly associated with violent & aggressive behavior, depression, & suicidal tendencies

5.  Proper Use of Essential Fats:  They are needed for the proper utilization of essential fatty acids. Elongated omega 3 fatty acids are better retained in the tissues when the diet is rich in saturated fats.

6.  Fuel For the Heart:  Saturated 18-carbon stearic acid and 16-carbon palmitic acid are the preferred foods for the heart, which is why the fat around the heart muscle is highly saturated.  The heart draws on this reserve of fat in times of stress.

7.  Anti-Microbial Properties:  Short- and medium-chain saturated fatty acids have important antimicrobial properties. They protect us against harmful microorganisms in the digestive tract.   Cholesterol plays a vital role in the repair and maintenance of the intestinal wall, preventing leaky gut syndrome, ulcerative colitis, and a host of other intestinal disorders.

8.  Anti-Oxidant Protection:  Cholesterol is now understood to be a vital anti-oxidant that protects us from free radical damage and helps to heal any arterial damage that may have occurred.  Higher levels of free radical damage from oxidative stress = higher levels of circulating cholesterol.

9.  Bile Production:  Cholesterol produces bile salts that help us metabolize fats in our diet.

10.  Brain and Nervous System Development:  Cholesterol is extraordinarily important for babies & children as they develop their brain and nervous system.  Over half of the brain is composed of saturated fats and cholesterol.  Interestingly, one of the richest sources of cholesterol is mother’s milk, which also contains a special enzyme that helps the baby metabolize and use this nutrient.

cholesterol myth, The Great Cholesterol Myth

Get the Real Story:

The cholesterol myth continues to confuse and mislead both doctors and the lay public today.  But the truth is that cholesterol is one of the most powerful healing foods and molecules your body can ingest and produce.  The problem lies in the oxidation of cholesterol from high levels of free radicals and high firing inflammatory pathways. The key to preventing and reversing heart disease is to put out the inflammatory fires.

If you want to know more about what to look for, such as LDL Pattern A and pattern B and what form of LDL is a problem than read this article here   What have you learned over the years in relationship to cholesterol and heart disease?  Would love to hear your comments.

cholesterol myth, The Great Cholesterol Myth

Sources For This Article Include:

1. Uemura K, Pisa Z. Trends in cardiovascular disease mortality in industrialized countries since 1950. World Health Stat Q. 1988;41(3-4):155-78. PMID: 3232406
2. CDC – Chronic Disease Overview Link Here
3. Ancel Keys and the lipid hypothesis: From early breakthroughs to current management of dyslipidemia Link Here
4. Ravnskov U. The fallacies of the lipid hypothesis. Scand Cardiovasc J. 2008 Aug;42(4):236-9. PMID: 18615352
5. Rosch PJ. Cholesterol does not cause coronary heart disease in contrast to stress. Scand Cardiovasc J. 2008 Aug;42(4):244-9. PMID: 18609060
6. Ravnskov U. A hypothesis out-of-date. the diet-heart idea. J Clin Epidemiol. 2002 Nov;55(11):1057-63. PMID: 12507667
7. “Healthy” Unsaturated Fats Link Here
8. The Skinny on Fats Link Here

cholesterol myth, The Great Cholesterol Myth

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  1. Good article, insightful in helpful to responding to the misinformation regarding Cholesterol concerns. What is the suggested healthful range as the numbers seem to change?

  2. You want your LDL:HDL ratio to be less than 3:1 and you want your triglyceride levels to be under your HDL levels.

    There are many other tests such as the VAP test and NMR that measure all the subsets of cholesterol and give us so much more information than a regular lipid panel.

  3. Hello Dr David
    Profoundly valuable information on cholesterol. Unfortunately, cholesterol myth is widely prevalent amongst conventionally trained doctors due erroneous teaching at medical schools then and now. They impart very bad image of word cholesterol as “Bad – cholesterol” and this word it-self purported as something dangerous?
    In context of recent researches and enormous work done by functional medicine and (conventionally trained pioneer like Dr William Davis and Dr David Perlmutter), lot of myths have broken down. Sincere thanks to all.
    I have gone through this article, being a conventionally trained doctor, I want to know any good book or websites to go in more simplified way for this topic, which can be shared with patients and their caregivers. Kindly suggest.
    Still a large section of population is tremendously scared of eating good fats even and they frequently query and are astonished about eating fats. This is on account of two perpetuating factors:
    1. Bad reputation about eating fat
    2. And contradictory opinion given by conventionally trained doctors and media.
    Dr Prakash Chhajed

    1. Hey Dr Prakash,

      I would recommend the Big Fat Lies video (youtube clip in this article) for lay people as it makes a really good impression and is easy to follow and entertaining. Blessings!

      1. Dr Jockers. I am from Malaysia. Recently i went for a medical Total Cholesterol is 7.7 mmol/l, HDL cholesterol is 1.17 mmol/l, LDL cholesterol is 5.5 mmol/l, Triglycerides is 2.2 mmol/l and the Total/HDL Ratio is 6.6. I need your help to understand this I really need to be concerned. I am confused..pls help..

  4. Gluten may cause the thyroid to go down and cholesterol to go up. Amour thyroid may lower the cholesterol. Many people don’t get thyroid medicine when it would help. No statin drug is needed it seems when the root causes are fixed.

  5. This is the first article I’ve read on the benefits of cholesterol. I was searching for “lowering cholesterol” in my inbox and this article popped up from several years ago! I just found out my total cholesterol is 255. Triglycerides 141, HDL 41, VLDL, 26, LDL Chol Calc (NIH) 188, LDL/HDL ratio 4.6. I’m trying to figure the ratio for healthy cholesterol. I also just discovered I’ve got a big gallstone (that’s inactive/no inflammation in the area). And on the positive my pancreas and liver look healthy and normal. Could the gallstone be a result of the high cholesterol? I’ve had high cholesterol since my 20s (I’m now 44). My diet has been off and on plant-based for decades now. I’m probably a good 10-15lbs overweight w/ digestion issues after taking antibiotics twice in the last 5 years. My diet is 80 percent anti-inflammatory (w/occasional sweet binges). My vitamin D levels are 11! With the encouragement of my holistic psychologist, I got lab work done. Now I understand the reason for the extreme fatigue, bone aches and random muscle cramps in toes and stomach I’ve had off and on for 2 years now! Not to mention anxiety and bouts of depression. Could the high cholesterol be the result of the severely low vitamin D ? From what I understand, we need cholesterol to make vitamin D. Since my diet is mostly healthy, how can I lower cholesterol? I do not exercise regularly – could daily exercise help improve numbers?

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