Episode #623: Longevity Secrets for Better Brain and Energy Levels as You Age with Dr. Isaac Jones

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Most people think longevity is about adding more years to life—but what if it’s really about adding more life to your years?

In this powerful episode, I have a great discussion with my best friend and longevity expert Dr. Isaac Jones to unpack what really drives aging—and how to stay sharp, energized, and vibrant as you get older.

Why We Age Faster Than We Should

Dr. Jones reveals how oxidative stress—essentially “internal rusting”—is one of the biggest culprits behind aging, brain fog, and fatigue.

He explains how lifestyle factors like stress, sleep, and diet can either fuel inflammation or protect against it. You’ll also learn about the hallmarks of aging, and how to interrupt the vicious cycle that accelerates cellular damage.

The Breakthrough Nutrients for Longevity

This conversation dives deep into the most cutting-edge nutrients that support mitochondrial health, boost brain energy, and extend your health span. From glutathione to PQQ and NAD+, Dr. Jockers and Dr. Jones break down the science behind how these powerful compounds help your body regenerate, detoxify, and perform at its best—no matter your age.

  • 00:00 Understanding Oxidative Stress and Aging
  • 02:34 Exploring Longevity and Aging
  • 03:20 Meet Dr. Isaac Jones: Longevity Expert
  • 04:16 Breakthrough Nutrients for Longevity
  • 06:20 The Role of Epigenetics in Aging
  • 08:12 Hallmarks of Aging and Their Impact
  • 12:50 The Importance of Mitochondrial Health
  • 18:57 Key Nutrients for Longevity
  • 24:20 Maintaining Muscle Mass for Longevity
  • 24:58 The Role of Gut Microbiome in Health
  • 26:00 The Power of Pomegranate Extract
  • 28:59 The Importance of Glutathione
  • 30:29 Understanding PFAS and Their Impact
  • 32:34 Creating a Synergistic Longevity Stack
  • 39:36 Innovative Supplement Delivery System
  • 44:23 Customizing Supplements for Individual Needs
  • 45:37 Conclusion and Final Thoughts

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Dr. Jockers

Dr David Jockers is passionate about seeing people reach their health potential in mind, body and spirit. He is the host of the popular “Dr Jockers Functional Nutrition” podcast and the author of the best-selling books, “The Keto Metabolic Breakthrough” and “The Fasting Transformation.”

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