If you’re dragging through the day, gaining weight despite eating “clean,” or feeling cold, anxious, or foggy, your thyroid might be getting blamed for something bigger.
In this episode, I sit down with Dr. Justin Marchegiani to explain why thyroid symptoms often start far upstream, and why fixing the metabolism conversation usually means looking beyond the thyroid labs. Check out Dr Marchegiani’s new book the Thyroid Reboot: Identify and Address Your Top 10 Symptoms in 30 Days.
The Real Metabolism Bottlenecks Most People Miss
Dr. Justin breaks down how thyroid hormone is supposed to work in the body, including the conversion process that turns T4 into active T3. Then they connect the dots to the real-world issues that can slow everything down: gut dysfunction, liver overload, chronic stress, inflammation, and nutrient gaps.
Translation: you can be doing “all the right things” and still feel stuck if your body can’t activate what it already has.
Blood Sugar, Stress, and Why Your Energy Crashes Keep Happening
This conversation gets practical fast. You’ll hear why insulin resistance and blood sugar swings can drag thyroid function down, and how stress can push glucose up even when you’re not eating.
They also share simple daily actions that can shift your numbers and your symptoms, without turning your life into a full-time wellness project.
A Smarter 30-Day Reset Starts With the Right Signals
If you’ve been told your labs are “normal” but you don’t feel normal, this episode will help you understand what to look at next. You’ll walk away with a clearer strategy for supporting thyroid function, calming metabolic chaos, and building momentum in a way that actually sticks. Press play and you’ll start seeing your symptoms through a completely different lens.
- 00:00 Sleep Deprivation, Cortisol & Blood Sugar Spikes
- 02:17 Meet Dr. Justin & Introducing ‘The Thyroid Reboot book
- 02:56 Why the Thyroid Matters: Metabolism, Gut, Immunity & Autoimmunity
- 04:13 Hyperthyroid vs Hypothyroid: TSH, T4/T3 Basics & Graves vs Hashimoto’s
- 08:25 Hypothyroid Symptom Checklist + Basal Temperature Clues
- 11:15 Thyroid Hormone Activation: TRH→TSH→T4→T3, Liver Conversion & Key Nutrients
- 16:39 Gut Microbiome, Estrogen Detox & Why Thyroid Is a Whole-Body Issue
- 19:18 Hair Growth Cycle Explained + Why Follicles Get “Stuck”
- 20:41 Root Causes of Hypothyroidism: Insulin Resistance, Stress, Diet Gaps
- 22:08 Toxins & Microplastics: How Endocrine Disruptors Impact Thyroid Hormones
- 22:43 Reading Thyroid Labs: Ideal TSH/T4/T3 Ranges & What They Mean
- 24:39 Treatment Strategy: Foundations First, Then Thyroid Support (If Needed)
- 26:53 DIY Thyroid Foundations: Diet, Blood Sugar Testing, Movement & Sleep
- 33:57 Wrap-Up: Book Plug, Where to Get Help, and Final Takeaways
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Connect with Dr. Justin Marchegiani:
- Book: https://amzn.to/41FtiJX
- Website: justinhealth.com
Connect with Dr. Jockers:
- YouTube
- Website
- If you are interested in being a guest on the show, we would love to hear from you! Please contact us here!
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