Episode #464: Understanding Cholesterol Dynamics and Metabolic Health with Dr. Nick Norwitz

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In This Episode:

In this interview with Dr. Nick Norwitz, we dive into his recent study published in January of 2024 in Metabolites that reviews his experiment showing that eating 12 Oreo cookies a day for 16 days and how this lowered his cholesterol significantly more than high dose statin drugs taken for 6 weeks.

We also review the lipid energy model and lean mass hyperresponders and how we should view cholesterol metabolism. Check out Dr. Norwitz website here.

In this enlightening podcast episode, Dr. Nick Norwitz dives deep into the complex world of cholesterol and its impact on metabolic health. If you’ve ever wondered whether the conventional wisdom around cholesterol truly applies to you, this episode will change the way you think about heart health.

The Surprising Results of the “Oreo vs. Statin” Study

One of the most provocative studies discussed in this episode is the groundbreaking “Oreo vs. Statin” experiment conducted by Dr. Norwitz. Imagine this: Oreo cookies lowering LDL cholesterol more effectively than high-dose statins.

Sounds crazy, right? Dr. Norwitz explains how this unconventional study sheds light on the complexities of cholesterol dynamics, especially for those on a ketogenic diet.

Why Understanding Your Unique Cholesterol Profile Matters

Not all cholesterol is created equal, and this episode emphasizes the importance of looking beyond traditional LDL metrics. Dr. Norwitz discusses why individual physiology plays a critical role in determining cardiovascular risk and why a personalized approach to cholesterol management is essential.

Don’t miss this eye-opening conversation that challenges everything you thought you knew about cholesterol and metabolic health. Listen to the full episode now and gain insights that could transform your understanding of heart health.

08:20 The Oreo Cookie Experiment
15:59 Exploring the Lean Mass Hyper Responder Phenomenon
34:43 Understanding VLDL and Triglyceride Metabolism
35:28 The Triad: LDL, HDL, and Triglycerides
36:36 Exploring the Lipid Energy Model
37:30 Insulin’s Role in Fat Metabolism
38:22 Clinical Data and Metabolic Profiles
41:20 The Controversy of LDL Particles
46:26 The Lean Mass Hyper Responder Phenotype
52:49 Personal Journey with Ketogenic Diet
58:01 Side Effects of Statin Drugs
01:02:20 Satiety Per Calorie and Marketing Tactics
01:07:47 Conclusion and Final Thoughts

“The physiology behind lean mass hyper-responders is an incredible natural experiment, a gift to science.”

-Dr. Nick Norwitz

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Dr. Jockers

Dr David Jockers is passionate about seeing people reach their health potential in mind, body and spirit. He is the host of the popular “Dr Jockers Functional Nutrition” podcast and the author of the best-selling books, “The Keto Metabolic Breakthrough” and “The Fasting Transformation.”

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