Episode #761: Top Foods, Nutrients and Peptides for Cellular Longevity with Dr. Josh Axe

Why do some people hit their 90s still hiking, traveling, and playing with grandkids, while others are old before their time?

I sit down with Dr. Josh Axe, co-founder of Ancient Nutrition and founder of draxe.com, to unpack the science of cellular longevity: how our cell membranes and mitochondria age, why one organ system often ages faster than the rest of the body, and what we can actually do about it through food, supplements, and lifestyle.  Check out Dr Josh Axe’s new book, Heal Your Cells.

The Best Foods for Cellular Longevity

Dr. Axe walks through his top food categories for longevity, starting with brightly colored super berries and fruits like goji, black currant, maqui, and pomegranate, prized for antioxidants like anthocyanins and ellagic acid that fight the oxidative stress and free radical damage that age our cells.

He explains how ellagic acid gets converted by gut bacteria like Akkermansia muciniphila into urolithin A, a compound tied to mitochondrial and cellular longevity, though only about 40% of people convert it efficiently, which is why gut health matters as much as the food itself.

From there, the conversation moves through colorful vegetables and cruciferous greens, organ meats as nature’s methylation and B-vitamin supplements, quality protein and healthy fats like wild-caught salmon and walnuts, high-polyphenol extra virgin fer, fermented foods like miso and sauerkraut, and longevity mushrooms such as reishi, lion’s mane, and cordyceps.

Top Supplements and Lifestyle Keys for Longevity

Dr. Axe shares his top longevity supplements, vitamin D, soil-based probiotics, omega-3s, and magnesium, while cautioning against low-quality, isolated nutrients like standalone calcium carbonate that can actually accelerate arterial aging.

Dr. Axe and I also discuss NAD/NMN, adaptogenic herbs, green and matcha tea, and the surprising longevity benefits of bee products, closing with a reminder that supplements are only a small piece of the puzzle: circadian rhythm, time outdoors, and daily habits like herbal tea do most of the heavy lifting.

• 00:00 Berry Powders Routine
• 00:14 Longevity Podcast Intro
• 04:02 What Is Cellular Longevity
• 04:52 Aging Organs and Cells
• 06:52 Cell Membranes and Mitochondria
• 09:26 Foods to Live Past 100
• 09:53 Super Berries for Longevity
• 13:18 Pomegranate and Urolithin A
• 17:24 Akkermansia and Ellagic Acid
• 19:00 Vegetables for Detox and Heart
• 20:35 Organ Meats and Methylation
• 23:44 Protein and Like Supports Like
• 25:37 Omega 3s and Healthy Fats
• 28:59 Oil Quality Over Smoke Point
• 29:18 Choosing High Polyphenol Olive Oil
• 30:19 Healthy Fats For Longevity
• 30:52 Fermented Foods And Gut Health
• 32:30 Longevity Mushrooms Explained
• 33:58 Longevity Foods Recap
• 34:42 Top Supplements Vitamin D
• 40:13 Probiotics Omega 3 And Quality
• 43:32 Avoiding Bad Supplements Calcium
• 44:21 NAD NMN And Supplement Impact
• 46:54 Magnesium Adaptogens And Green Tea
• 48:44 Bee Products And Venom Therapy
• 51:23 Herbal Tea Daily Ritual
• 52:28 Where To Find Dr Josh Axe
• 53:50 Final Thanks And Sign Off

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